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Smartphone-Controlled Cells help keep Diabetes in Check

Image shows bone progenitor cells labeled by red glow inside a cleared femur. Credit: A. Greenbaum et al., Science Translational Medicine (2017)

Image shows bone progenitor cells labeled by red glow inside a cleared femur. Credit: A. Greenbaum et al., Science Translational Medicine (2017)

Cells engineered to produce insulin under the command of a smartphone helped keep blood sugar levels within normal limits in diabetic mice. More than 415 million people worldwide are living with diabetes, and frequently need to inject themselves with insulin to manage their blood sugars. Human cells can be genetically engineered into living factories that efficiently manufacture and deliver hormones and signaling molecules, but most synthetic biological circuits don’t offer the same degree of sensitivity and precision as digital sensors.

Combining living tissues and technology, Jiawei Shao et al...

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