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    immune response tagged posts

    Previously unrecognized immune response could enhance defense against cancer

    April 13, 2026, Categories  Biology/Biotechnology, Health/Medical

    In a paradigm-breaking study, researchers have discovered a novel way the immune system, specifically Tcells, attack their target cells, reshaping long-held assumptions in immunology and demonstrating direct implications for the field of cancer immunology and bone marrow transplantation. The team consists of Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S P Hicks Endowed Professor of Pathology, and Marcin Cieslik, assistant professor of pathology, both from University of Michigan Rogel Cancer Center. The study is published in Nature Immunology.

    Rewriting the rules of T cell biology
    The immune system relies on molecules called major histocompatibility complexes (M...

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    Common Immune Response is found to be Protective Across Many Diseases

    March 5, 2024, Categories  Health/Medical, Biology/Biotechnology

    Common immune response protective across many diseases
    Overview of study design, analytic methods, and dataset multi-omics. (A) Cartoon describing the collected single-cell and bulk multi-omic datasets with paired clinical data from infection, autoimmunity, and cancer contexts. (B) Cartoon depicting experimental and analytic strategies for single-cell and bulk data with a focus on NKG2A/C-expressing cell types. (C) Cartoon demonstrating NKG2A+ and NKG2C+ bias assignment at single-cell and bulk levels. (D) Cartoon displaying the different clinical and biological -omics to be compared between NKG2A+ and patients with an NKG2C+ bias. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.113872

    Combined, infection, autoimmunity and cancer account for 4 out of every 10 deaths worldwide, and represent major global health challenges...

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    Scientists Reveal How our Cells’ Leaky Batteries are making us Sick

    March 5, 2024, Categories  Biology/Biotechnology, Health/Medical

    X ray of painful hands
    Rheumatoid arthritis is a chronic inflammatory condition that can damage joints.

    The new findings could lead to better treatments for rheumatoid arthritis, lupus and other inflammatory diseases – and may even help us slow aging.

    Researchers have discovered how “leaky” mitochondria can drive harmful inflammation responsible for diseases such as lupus and rheumatoid arthritis. Scientists may be able to leverage the findings to develop better treatments for those diseases, improve our ability to fight off viruses and even slow aging.

    The new discovery reveals how genetic material can escape from our cellular batteries, known as mitochondria, and prompt the body to launch a damaging immune response...

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    Researchers find a New Class of Biomarkers to Predict Treatment Outcomes in Cancer Patients

    June 26, 2023, Categories  Health/Medical, Biology/Biotechnology

    Researchers find a new of biomarkers to predict treatment outcomes in cancer patients
    Cancer is the result of the uncontrolled division and spread of cells into surrounding tissue. Recently researchers have begun to focus on biomarkers as a source of information about different cancers, how they work in the body, and how they can be fought. Credit: Colin Behrens/Pixabay, CC0 Public Domain

    One of the big reasons that cancer is difficult to treat is that patients respond to treatments differently, and these differences can rarely be anticipated. In most cases, determining whether and how a patient will respond to any given therapy requires administering it to the patient and then waiting and watching. That is a lot of pressure for researchers and physicians and a lot of risk for cancer patients, and added expense.

    If a patient’s response were predictable, optimal thera...

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