immune system tagged posts

New Treatment Stops Progression of Alzheimer’s disease in Monkey Brains

Rendering of Tau Protein in Alzheimer's Disease
PHOTO: JUAN GAERTNER/SCIENCE PHOTO LIBRARY/GETTY

A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer’s disease, a new study shows.

Led by researchers at NYU Grossman School of Medicine, the investigation showed that elderly monkeys had up to 59 percent fewer plaque deposits in their brains after treatment with CpG oligodeoxynucleotides (CpG ODN), compared with untreated animals. These amyloid beta plaques are protein fragments that clump together and clog the junctions between nerve cells (neurons).

Brains of treated animals also had a drop in levels of toxic tau...

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New link between Personality and Risk of Early Death

Dr Páraic Ó Súilleabháin, from the Department of Psychology and Health Research Institute at University of Limerick, who was principal investigator on the study

Ground-breaking research led by University of Limerick has revealed for the first time that the immune system directly links personality to long-term risk of death. The study sheds new light on why people who are more conscientious tend to live longer.

Results from the new international study published in the journal Brain, Behavior, and Immunity have found that the immune system plays a previously unknown role in the link between personality traits and long-term risk of death.

“Personality is known to be associated with long-term risk of death, it is a well replicated finding observed across numerous research studies...

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Polysaccharides from Red Algae affect Mice Immune systems, say scientists

After adding carrageenans to the diet of lab mice for one week, the activity of their congenital immunity cells reduced and leukocyte count dropped. Image is in the public domain

Carrageenans, biologically active polysaccharides isolated from red algae and widely used in the food industry as stabilizers, thickeners, or jelly agents, have an express effect on the immune systems of mice, according to a new study. The research was carried out by scientists from the School of Biomedicine of Far Eastern Federal University (FEFU), Far Eastern Branch of the Russian Academy of Sciences, and Vilnius University. A related article appears in the Journal of Biomedical Materials Research.

“The fact that carrageenan demonstrates immunosuppressive properties in a particular case does not make it g...

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Scientists build whole functioning Thymus from Human Cells

Images of stages of the researchers repopulating the scaffold.

Scientists at the Francis Crick Institute and University College London have Rebuilt a human Thymus, an essential organ in the Immune system, using human stem cells and a bioengineered scaffold. Their work is an important step towards being able to build artificial thymi which could be used as transplants.

The thymus is an organ in the chest where T lymphocytes, which play a vital role in the immune system, mature. If the thymus does not work properly or does not form during fetal development in the womb, this can lead to diseases such as severe immunodeficiency, where the body cannot fight infectious diseases or cancerous cells, or autoimmunity, where the immune system mistakenly attacks the patient’s own healthy tissue.

In their proof-of-concept study, published in Nature Comm...

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