inflammatory bowel diseases (IBD) tagged posts

How Microbiome is disrupted during IBD: Human Microbiome Project

A chart showing interactions between human and gut microbial features during inflammatory bowel disease.
A depiction of interactions between human and gut microbial features during inflammatory bowel disease.

A new study led by researchers from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard is the first to have observed the complex set of chemical and molecular events that disrupt the microbiome and trigger immune responses during flare-ups of inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis.

While previous studies have cataloged microbial changes during IBD, the researchers in this study developed a unique biotechnology toolbox to understand why microbiomes change during IBD and how this provokes an unhealthy inflammatory reaction...

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