Interleukin IL2 combined with #imiquimod and topical retinoid therapy tagged posts

New Combination Rx effective against Melanoma Skin Metastases

Metastatic melanoma: positron emission tomographic (PET)/computed tomography (CT) images. A-C, PET/CT of the head and neck after recurrence of malignant melanoma reveals increased FDG uptake spanning from the nose, left malar cheek, to the left ear, which represents a large melanoma (8.5 cm) and multiple additional in-transit metastases. E-G, Three months after restarting intralesional interleukin 2, imiquimod, and a topical retinoid, there is resolution of the enhancing lesions. D, At initial presentation, PET/CT image (patient 8) shows increased FDG uptake in the skin and subcutaneous tissues of the back of right forearm, consistent with biopsy-proven melanoma (18- × 6-cm plaque). H, At 5 months posttreatment, no hypermetabolic lesion is identified.

Metastatic melanoma: positron emission tomographic (PET)/computed tomography (CT) images. A-C, PET/CT of the head and neck after recurrence of malignant melanoma reveals increased FDG uptake spanning from the nose, left malar cheek, to the left ear, which represents a large melanoma (8.5 cm) and multiple additional in-transit metastases. E-G, Three months after restarting intralesional interleukin 2, imiquimod, and a topical retinoid, there is resolution of the enhancing lesions. D, At initial presentation, PET/CT image (patient 8) shows increased FDG uptake in the skin and subcutaneous tissues of the back of right forearm, consistent with biopsy-proven melanoma (18- × 6-cm plaque). H, At 5 months posttreatment, no hypermetabolic lesion is identified. Creit: 10.1016/j.jaad.2015.06.060

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