Internal Clocks tagged posts

Internal Clocks drive Beta Cell Regeneration

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Image of pancreatic islets showing proliferation markers (in red staining) in the nuclei (in blue) of insulin-producing-cells (in green).  © UNIGE/Dibner

Certain parts of our body, such as the skin or liver, can repair themselves after a damage. For the past 30 years, scientists have been investigating the regenerative potential of beta cells, pancreatic cells in charge of the production of insulin. Beta-cell population is indeed partially destroyed when diabetes occurs, and regenerating these cells represents an outstanding clinical challenge.

By studying diabetic mice, scientists from the University of Geneva (UNIGE) and the University Hospitals of Geneva (HUG, observed that this regeneration mechanism was under the influence of circadian rhythms — the molecular clocks regulatin...

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