New Northwestern Medicine research published in Nature Communications suggests that a metabolite produced by gut bacteria when they digest dietary fiber can leave a lasting molecular imprint on intestinal cells, promoting immune tolerance and protecting against inflammatory bowel disease-like conditions long after exposure ends.
Yingzi Cong, Ph.D., the Stanley Gradowski Professor of Gastroenterology and a professor of Microbiology-Immunology and Pathology, was the senior and co-corresponding author of the study.
Investigators describe the findings as evidence that beneficial microbial metabolites may be able to “train” the intestinal lining to maintain immune tolerance over time.
“Our laboratory has...
Read More
Recent Comments