kidney disease tagged posts

The risk of developing chronic kidney disease (CKD) or heart failure (HF), or dying, following a type 2 diabetes (T2D) diagnosis increases substantially over time, according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2.

The study, which analyzed data from more than 1.6 million patients across the U.S., found that the combined risk of developing CKD or HF, or dying, was 33% on average within the first five years of a T2D diagnosis, rising to 55% over 10 years.

The researchers say their findings underscore the importance of early, proactive and more holistic approaches to managing type 2 diabetes to help reduce the risk of serious complications...

Kidney glomeruli — constituent microscopic parts of the organ- were generated from human embryonic stem cells grown in plastic laboratory culture dishes. Credit: Image courtesy of University of Manchester

Scientists have successfully produced human kidney tissue within a living organism which is able to produce urine, a first for medical science. It signifies a significant milestone in the development of treatment for kidney disease. Kidney glomeruli – constituent microscopic parts of the organ- were generated from human embryonic stem cells grown in plastic laboratory culture dishes containing a nutrient broth known as culture medium, containing molecules to promote kidney development...

CD24 expressed by cells of hematopoietic origin and not cells in stromal compartments is required for extramedullary stress erythropoiesis following in vivo CD24 engagement

This could represent a significant step forward in the battle against anemia, benefitting people with diabetes, kidney disease or cancer, and older people for whom anemia can become a chronic problem. While more work needs to be done before the method could be used in people, the possibilities are tantalizing.

Eg it could allow doctors to turn on red blood cell production whenever necessary;
~be used on the battlefield to triage wounded soldiers until they could receive a blood transfusion; and
~be used to treat people who cannot receive blood transfusions because of religious beliefs.

Note: Anemia is the most common bl...