light chain amyloidosis tagged posts

An engineering team at Washington University in St. Louis says a compound found in green tea may be of particular benefit to patients struggling with multiple myeloma and amyloidosis. Aggregation of Full Length Immunoglobulin Light Chains from AL Amyloidosis Patients Is Remodeled by Epigallocatechin-3-gallate. Journal of Biological Chemistry, 2016; jbc.M116.750323 DOI: 10.1074/jbc.M116.750323

Epigallocatechine-3-gallate (EGCG), a polyphenol found in green tea leaves, may be of particular benefit to patients struggling with multiple myeloma and amyloidosis. These patients are susceptible to a frequently fatal condition called light chain amyloidosis, in which parts of the body’s own antibodies become misshapen and can accumulate in various organs, including the heart and kidneys...