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    Microscope can Scan Tumors during Surgery and Examine Cancer Biopsies in 3D

    June 26, 2017, Categories  Health/Medical, Biology/Biotechnology

    This comparison shows images of breast tissue taken by the open-top light-sheet microscope (left), traditional pathology techniques (middle) and frozen sectioning during surgery (right). The first two images reveal crisp details of cellular and nuclear features, while the frozen-section image is distorted due to the challenges of freezing fatty breast tissues. While the formalin-fixed paraffin-embedded section requires hours of preparation, the open-top light-sheet microscope image is captured in minutes. Credit: Glaser et al., Nature Biomedical Engineering

    This comparison shows images of breast tissue taken by the open-top light-sheet microscope (left), traditional pathology techniques (middle) and frozen sectioning during surgery (right). The first two images reveal crisp details of cellular and nuclear features, while the frozen-section image is distorted due to the challenges of freezing fatty breast tissues. While the formalin-fixed paraffin-embedded section requires hours of preparation, the open-top light-sheet microscope image is captured in minutes. Credit: Glaser et al., Nature Biomedical Engineering

    Currently there’s no reliable way to determine during surgery whether the excised tissue is completely cancer-free at its margins – the proof that doctors need to be confident that they removed all of the tumor...

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