Peptides derived from Ov-GRN-1 (orthologue of granulin) are leads for wound healing therapeutics, as they are likely less immunogenic than the full-length protein and more convenient to produce.
A molecule produced by a Thai liver parasite could be the solution to those non-healing wounds. Globally, every 30 seconds a diabetic has a limb amputated due to a non-healing wound. Scientists from the Australian Institute of Tropical Health and Medicine (AITHM) are now able to produce a version of the molecule on a large enough scale to make it available for laboratory tests and eventually clinical trials. The molecule is granulin, one of a family of protein growth factors involved with cell proliferation.
“It’s produced by a parasitic liver fluke, Opisthorchis viverrini, which originally came to...
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