liver sinusoidal endothelial cells (LSECs) tagged posts

Treatment revives old liver cells in lab study, may help prevent Alzheimer’s and heart disease

Treatment revives old liver cells in lab study, may help prevent Alzheimer's and heart disease
Images of liver cells from aged rats elucidate cellular crosstalk in the liver. Credit: DeLeve Lab/USC

The liver’s job of clearing harmful substances from the body is so essential that the organ may have implications for addressing unexpected diseases, including Alzheimer’s and heart disease. A promising example comes from new Keck School of Medicine of USC research published in the Journal of Biological Chemistry.

The study, conducted in aged rats, shows that an experimental drug called cinaciguat reverses effects of aging in the liver. This, in turn, may lower the risk of Alzheimer’s disease and clogged arteries...

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