measuring different metabolites simultaneously tagged posts

New method measures Single Molecules from Nanoliter of Blood in Real Time

A nanopore device can contain different binding proteins. Once inside the pore, these proteins act as transducers to identify specific small molecules in a sample of body fluid.
Credit
Giovanni Maglia, University of Groningen

Scientists have designed a nanopore system that is capable of measuring different metabolites simultaneously in a variety of biological fluids, all in a matter of seconds. The electrical output signal is easily integrated into electronic devices for home diagnostics.

Measuring many metabolites or drugs in the body is complicated and time-consuming, and real-time monitoring is not usually possible. The ionic currents that pass through individual nanopores are emerging as a promising alternative to standard biochemical analysis...

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