
Prefrontal cortex shapes memory formation by modulating hippocampal encoding
Neurons in the prefrontal cortex “teach” neurons in the hippocampus to “learn” rules that distinguish memory-based predictions in otherwise identical situations, suggesting that learning in the present helps guide learning in the future, according to research conducted at the Icahn School of Medicine at Mount Sinai and published April 5 in the journal Neuron. The study investigated memory flexibility and interference, the mechanisms by which the brain interprets events and anticipates their likely outcomes. The hippocampus is a temporal lobe brain structure for remembering recent events...
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