Postdoc Jinsen Chen, left, and chemistry professor Shiyue Fang in the lab where Fang’s group discovered a new way to synthesize DNA. Credit: Michigan Tech
Michigan Technological University scientists have developed a process that could lead to stickier and better gene therapy drugs. The drugs, called antisense DNA, are made from short, single strands of synthetic DNA. They work by blocking cells from making harmful proteins, which can cause maladies ranging from cancer to Ebola to HIV-AIDS. Only a couple of these synthetic DNA drugs are on the market, but a number are in clinical trials, including a potential treatment for ALS.
Disease organisms can inject harmful proteins into our bodies, and so can mutations in our own genetic material...
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