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Targeted Treatment could prevent spread of Pancreatic cancer, Heart Damage

Pancreatic cancer cells, under a microscope. Credit: University of Cincinnati

Pancreatic cancer cells, under a microscope. Credit: University of Cincinnati

Researchers at the University of Cincinnati (UC) College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer and protecting their heart from damage – a direct result of the tumor. Higher levels of serotonin among other tumor secretions can cause injury to the valves of the heart over time, leading to cardiac impairment – a condition referred to as cardiac carcinoid disease – in these patients.

These findings, reported in the November 2017 issue of Molecular Cancer Therapeutics, could lead to another targeted treatment for patients and prevent the onset of additional complications from their cancer...

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