multi-drug resistant Shigella infections tagged posts

Harnessing the power of Predatory Bacteria as a ‘Living Antibiotic’

Highlights SIP is a new protein phosphatase 2A-containing protein complex SIP is essential for the asymmetric localization of SIN components to the SPB SIP is required for the SPB localization of the SIN inhibitor Byr4p SIP promotes dephosphorylation of the SIN scaffold protein Cdc11p

Highlights SIP is a new protein phosphatase 2A-containing protein complex SIP is essential for the asymmetric localization of SIN components to the SPB SIP is required for the SPB localization of the SIN inhibitor Byr4p SIP promotes dephosphorylation of the SIN scaffold protein Cdc11p

A naturally occurring predatory bacterium is able to work with the immune system to clear multi-drug resistant Shigella infections in zebrafish. It is the first time the predatory bacterium Bdellovibrio bacteriovorus has been successfully used as an injected anti-bacterial therapy and represents an important step in the fight against drug-resistant infections, or ‘superbugs’.

Shigella infection is responsible for over 160 million illnesses and over 1 million deaths every year – and is a common cause of ‘trave...

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