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Smoking a Pack a Day for a Year causes 150 Mutations in Lung Cells

Genetic damage caused by smoking measured in different organs of the body

Genetic damage caused by smoking measured in different organs of the body

Genetic damage caused by smoking measured in different organs of the body. Scientists have measured the catastrophic genetic damage caused by smoking in different organs of the body and identified several different mechanisms by which tobacco smoking causes mutations in DNA. Researchers at the Wellcome Trust Sanger Institute, the Los Alamos National Laboratory and their collaborators found smokers accumulated an average of 150 extra mutations in every lung cell for each year of smoking one packet of cigarettes a day. The study provides a direct link between the number of cigarettes smoked in a lifetime and the number of mutations in the tumour DNA...

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