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Fast, Efficient Sperm Tails Inspire Nanobiotechnology

Graphic depicts the tethered enzymes and free-floating enzymes. Credit: Cornell University

Graphic depicts the tethered enzymes and free-floating enzymes. Credit: Cornell University

Just like workers in a factory, enzymes can create a final product more efficiently if they are stuck together in one place and pass the raw material from enzyme to enzyme, assembly line-style. That’s according to scientists at Cornell’s Baker Institute for Animal Health, the first team to recreate a 10-step biological pathway with all the enzymes tethered to nanoparticles. They were inspired to study how nanoparticles could gain biological functions through the enzymes that drive sperm tails, which turn sugar into lactate and energy so quickly that sperm can speed along at 5 body lengths/s

“Sperm have a highly efficient energy-producing system,” said Chinatsu Mukai, a postdoctoral research associate...

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