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    Tubulin prevents toxic protein clumps in the brain, fighting back against neurodegeneration

    March 10, 2026, Categories  Health/Medical, Biology/Biotechnology

    Tubulin prevents toxic protein clumps in the brain, fighting back neurodegeneration
    WT Tau/αSyn Endogenous Colocalization in Cells and Tau/αSyn/Tubulin Confocal Phase Diagram. Credit: Nature Communications (2026). DOI: 10.1038/s41467-026-69618-3

    Researchers at Baylor College of Medicine have discovered a potential new strategy to fight back against Alzheimer’s and Parkinson’s diseases, conditions that are linked to the toxic accumulation of Tau and alpha synuclein protein clumps in the brain. The team reports in Nature Communications that tubulin, the building block of microtubules, the cell’s internal ‘railway tracks,” can stop Tau and alpha synuclein from forming toxic clumps and instead steer them into their normal, healthy roles.

    “Tau and alpha synuclein are well known for their roles in neurodegenerative diseases like Alzheimer’s and Parkinson’s...

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    High-Intensity Exercise can Reverse Neurodegeneration in Parkinson’s, study suggests

    February 29, 2024, Categories  Uncategorized

    Dopamine Transporter Levels Pre- and Post-Exercise. A Average 18F-FE-PE2I DAT BPND images before and after six months of exercise. The red box including the midbrain and SN is enlarged. B 18F-FE-PE2I BPND in the SN pre- and post-exercise by study participant. Individual lines are red if an increase was observed, blue if a decrease was observed. The solid black line represents the mean of our cohort, the dashed black line represents the expected decrease from the pre-exercise average in the absence of intervention. Credit: npj Parkinson’s Disease (2024). DOI: 10.1038/s41531-024-00641-1

    High-intensity exercise induces brain-protective effects that have the potential to not just slow down but possibly reverse the neurodegeneration associated with Parkinson’s disease, a new pilot ...

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    Gut Bacteria affect Brain Health, Mouse study shows

    January 13, 2023, Categories  Health/Medical, Biology/Biotechnology

    Gut bacteria can influence brain health, according to a study of mice genetically predisposed to develop Alzheimer’s-like brain damage. The study, by researchers at Washington University School of Medicine in St. Louis, indicates that gut bacteria produce compounds that influence the behavior of immune cells, including ones in the brain that can cause neurodegeneration. The findings suggest a new approach to treating Alzheimer’s and other neurodegenerative diseases. Getty Images

    Findings suggest new approach to treating Alzheimer’s, other neurodegenerative diseases. Gut bacteria can influence brain health, according to a study of mice genetically predisposed to develop Alzheimer’s-like brain damage...

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    Type 2 Diabetes Accelerates Brain Aging and Cognitive Decline

    May 26, 2022, Categories  Health/Medical, Biology/Biotechnology

    Aging effects on the brain, further exacerbated in type 2 diabetes. Image credit: Lilianne Mujica-Parodi (CC BY 4.0)

    Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.

    The authors evaluated the relationship between typical brain aging and that seen in type 2 diabetes, and observed that type 2 diabetes follows a similar pattern of neurodegeneration as aging, but which progresses faster. One important implication of this finding is that even typical brain aging may reflect changes in the brain’s regulation of glucose by insulin.

    The results further suggest that by the time type 2 diabetes is formally diagnosed, the...

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