
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
Elderly to feel fitter, faster and stronger. Researchers from The University of Texas Medical Branch at Galveston have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a study just published in Biochemical Pharmacology.
As we age, our bodies increasingly lose the ability to repair and rebuild degenerating skeletal muscles. Beginning around age 35, muscle mass, strength and function continually decline as we get older. This can dramatically limit the ability of older adults to live fully active and independent lives.
“We identified a protein in m...
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