Anti-diabetic action of all-trans retinoic acid and the orphan G protein coupled receptor GPRC5C in pancreatic β-cells
A new study suggests that vitamin A improves the insulin producing β-cell´s function. The researchers initially discovered that insulin-producing beta-cells contain a large quantity of a cell surface receptor for vitamin A. “There are no unnecessary surface receptors in human cells. They all serve a purpose but which, in many cases, is still unknown and because of that they are called “orphan” receptors...
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