Overdoses from opioids like painkillers might become a thing of the pas–a vaccine to combat drug overdose is on the horizon. Eric Norris via Flickr, CC by 2.0
Scientists TSRI have developed a vaccine that blocks the pain-numbing effects of the opioid drugs oxycodone (oxy) and hydrocodone (hydro) in animal models. The vaccine also appears to decrease the risk of fatal opioid overdose, a growing cause of death in the United States. “We saw both blunting of the drug’s effects and, remarkably, prevention of drug lethality,” said Prof. Kim D. Janda.
MOA: The new oxy/hydro vaccine takes advantage of the immune system’s ability to recognize, seek out and neutralize invaders. Opioids were designed to reach receptors in the brain, causing pain reduction and feelings of euphoria...
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