A drug already licensed for the treatment of breast and ovarian cancer effects of chemotherapy, can target an Achilles heel in prostate cancers with a weakness in their ability to repair damaged DNA. It is now on the verge of becoming approved as the first genetically targeted treatment for prostate cancer.
This precision medicine drug, a type of treatment called a PARP inhibitor which specifically targets cancer cells with faulty DNA repair genes, blocked prostate cancer growth more effectively than the modern targeted hormone treatments abiraterone and enzalutamide.
The final results from the PROfound trial, published in the journal the New England Journal of Medicine today (Tuesday), are...
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