Figure 1. Radiologic Images of the Patient’s Liver and Phosphoinositide 3-Kinase (PI3K) Expression in the Patient’s Tumor Cells.
Metastatic Merkel-cell carcinoma is often fatal and there is no effective treatment. Now a researcher is reporting some positive results from treating this illness with a drug called idelalisib. Gao’s 86-year-old female patient was diagnosed in 2013 with stage IIIB Merkel-cell carcinoma of the right temple. She had surgery and received radiation therapy in May 2013 and additional surgery in Jul 2014. In Nov 2014 the cancer had metastasized.
Gao, a dermatologist who treats Merkel-cell carcinoma patients from Arkansas and surrounding states, performed genetics tests on the tumor that revealed multiple mutations, including PI3Kδ...
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