pirfenidone tagged posts

Scientists ID Source of Damaging Inflammation after Heart Attack

In this image of heart tissue, a single cardiac B cell lymphocyte is visible (blue surrounded by bright red). This type of immune cell triggers damaging inflammation after a heart attack, according to researchers at Washington University School of Medicine in St. Louis. Their study also shows that the drug pirfenidone

In this image of heart tissue, a single cardiac B cell lymphocyte is visible (blue surrounded by bright red). This type of immune cell triggers damaging inflammation after a heart attack, according to researchers at Washington University School of Medicine in St. Louis. Their study also shows that the drug pirfenidone

Existing drug dials down inflammation in mice. Scientists have zeroed in on a culprit that spurs damaging inflammation in the heart following a heart attack. The guilty party is a type of immune cell that tries to heal the injured heart but instead triggers inflammation that leads to even more damage.

Further, the researchers have found that an already approved drug effectively tamps down such inflammation in mice, protecting the heart from the progressive damage that often o...

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