Compared with a normal mouse cochlea (top), cisplatin exposure reduces the number of outer hair cells (middle). But the loss of these cells is prevented by treatment with the CDK2 inhibitor kenpaullone (bottom). Credit: Teitz et al., 2018
Researchers from St. Jude Children’s Research Hospital have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 (CDK2) protects mice and rats from noise- or drug-induced hearing loss. The study, which will be published March 7 in the Journal of Experimental Medicine, suggests that CDK2 inhibitors prevent the death of inner ear cells, which has the potential to save the hearing of millions of people around the world.
According to the World Health Organization, 360 million people worldwide, including 32 million children, suffer from hearin...
Read More
Recent Comments