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    A Noninvasive Test to Detect Cancer Cells and Pinpoint their Location

    July 20, 2021, Categories  Health/Medical, Biology/Biotechnology

    nanosensors detecting tumor microenvironment
    Multimodal nanosensors (1) are engineered to target and respond to hallmarks in the tumor microenvironment. The nanosensors provide both a noninvasive urinary monitoring tool (2) and an on-demand medical imaging agent (3) to localize tumor metastasis and assess response to therapy.
    Credits:Image: Liangliang Hao

    Most of the tests that doctors use to diagnose cancer—such as mammography, colonoscopy, and CT scans—are based on imaging. More recently, researchers have also developed molecular diagnostics that can detect specific cancer-associated molecules that circulate in bodily fluids like blood or urine.

    MIT engineers have now created a new diagnostic nanoparticle that combines both of these features: It can reveal the presence of cancerous proteins through a urine test, and it fu...

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