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New Zika Vaccine candidate protects Mice and Monkeys with a Single Dose

Study highlights mRNA-based vaccines and therapies. A new Zika vaccine candidate has the potential to protect against the virus with a single dose, according to a research team led by scientists from the Perelman School of Medicine at the University of Pennsylvania. As reported in Nature this week, preclinical tests showed promising immune responses in both mice and monkeys. “We observed rapid and durable protective immunity without adverse events, and so we think this candidate vaccine represents a promising strategy for the global fight against Zika virus,” said Drew Weissman, MD, PhD, a professor of Infectious Disease at Penn. “We hope to start clinical trials in 12 to 18 months.”

Prompted by the recent Zika virus outbreaks in Latin America and some parts of the United States, scientis...

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