
Kenneth Dill, right, and co-authors Adam de Graff, left, and Michael Hazoglou, center, standing beside a computerized display of three identified proteins at risk for oxidation: (Left) – A normal protein that has a balance of charges not at risk for oxidation; (Center) – The RBAp48 protein is at risk because of a high negative charge (red area), which are histones known in memory loss. (Right) – Telomerase protein is at risk for oxidation because of high net positive charge (blue area). Credit: John Griffin, Stony Brook University
When people turn about 80 yo, ~half of the body’s proteins are damaged by oxidation. Oxidation occurs because of random chemical degradations that are associated with converting food to energy in the presence of oxygen...
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