
Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A2 and Azaspirofuran A
New treatments for epilepsy are sorely needed because current medications don’t work for many people with the disease. To find new leads, researchers have now turned to the sea – a source that has been largely untapped for prospective drugs. 2 metabolites produced by a fungus from the Red Sea look promising. “Epilepsy” covers a spectrum of brain disorders with symptoms ranging from mildly odd sensations to seizures, loss of consciousness and death. Worldwide, the condition affects 50 million people, according to the World Health Organization. Current treatments work in only about 70% of those who try them.
Marcel Jaspars, Peter A. M...
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