Fundamental scientific discovery could lead to new ways to repair damaged hearts. University of Calgary researchers are the first to discover a previously unidentified cell population in the pericardial fluid found inside the sac around the heart. The discovery could lead to new treatments for patients with injured hearts. The study led by Drs. Paul Kubes, PhD, Justin Deniset, PhD and Paul Fedak, MD, PhD is published in the journal Immunity.
The Kubes lab, in collaboration with the Fedak lab, found that a specific cell, a Gata6+ pericardial cavity macrophage, helps heal an injured heart in mice. The cell was discovered in the pericardial fluid (sac around the heart) of a mouse with heart injury...
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