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New class of Molecular ‘Lightbulbs’ illuminate MRI

Duke scientists have discovered a new class of inexpensive and long-lived molecular tags that enhance MRI signals by 10,000-fold. To activate the tags, the researchers mix them with a newly developed catalyst (center) and a special form of hydrogen (gray), converting them into long-lived magnetic resonance 'lightbulbs' that might be used to track disease metabolism in real time. Credit: Thomas Theis, Duke University

Duke scientists have discovered a new class of inexpensive and long-lived molecular tags that enhance MRI signals by 10,000-fold. To activate the tags, the researchers mix them with a newly developed catalyst (center) and a special form of hydrogen (gray), converting them into long-lived magnetic resonance ‘lightbulbs’ that might be used to track disease metabolism in real time. Credit: Thomas Theis, Duke University

Discovery could enable cheaper, more versatile bioimaging. Duke University researchers have taken a major step towards realizing a new form of MRI that could record biochemical reactions in the body as they happen. A new class of molecular tags enhance MRI signals by 10,000-fold and generate detectable signals that last over an hour...

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