self-curving cornea tagged posts

Cultivating 4D Tissues: The Self-curving Cornea

The cornea moulds itself into a bowl-like structure over the course of 5 days. A three component gel comprising collagen, corneal stromal cells and peptide amphiphiles (inner circle) is combined with a two component gel comprising collagen and corneal stromal cells (outer circle). When triggered with a serum containing growth factors the outer ring of cells contracts more than the inner ring resulting in the progressive curvature of the structure.
Credit: Screen shot captured from video copyright 2019, Wiley-VCH

Scientists at Newcastle University have developed a biological system which lets cells form a desired shape by moulding their surrounding material – in the first instance creating a self-curving cornea...

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