Cardiomyocyte‐Specific Telomere Shortening is a Distinct Signature of Heart Failure in Humans. Journal of the American Heart Association, September 2017 DOI: 10.1161/JAHA.116.005086
Each cell in the body has 23 pairs of chromosomes, with 4 telomeres on each pair covering the end, protecting it from deterioration or fusion with adjacent chromosomes. While there is a length range for a healthy telomere, research found for the first time that people with heart failure have shorter telomeres in cardiomyocytes.
A team of researchers from Penn Medicine, in collaboration with the University of Connecticut, is the first to have developed a method for measuring the length of telomeres using human heart tissues...
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