Shutting Down Key Genes tagged posts

Regrowing Damaged Nerves Hinges on Shutting Down Key Genes


Mouse neurons are shown with the cell bodies in the center and long tendrils radiating outward. Valeria Cavalli, PhD, of Washington University School of Medicine in St. Louis, used such neurons to study how cells regrow after injury. Her findings could one day lead to better treatments for spinal cord injury.

Injured neurons temporarily revert to immature state. Neurons in the brain and spinal cord don’t grow back after injury, unlike those in the rest of the body. Cut your finger, and you’ll probably be back to using it in days or weeks; slice through your spinal cord, and you likely will never walk again.

Now, working in mice, researchers at Washington University School of Medicine in St...

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