Lee et al. show that hair follicles can be generated from mouse pluripotent stem cells in a 3-D cell culture system. The hair follicles (red) grow radially out of spherical skin organoids and contain follicle-initiating dermal papilla cells (green cells) and hair shafts (cyan). Credit: Artwork by Jiyoon Lee and Karl Koehler
Researchers at Indiana University School of Medicine have successfully developed a method to grow hairy skin from mouse pluripotent stem cells – a discovery that could lead to new approaches to model disease and new therapies for the treatment of skin disorders and cancers. This research marks the first demonstration that hair follicles can be grown in cultures of stem cells.
“The skin is a complex organ that has been difficult to fully recreate and maintain in culture ...
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