somatic cells tagged posts

1. Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells. Developmental Cell, 2019; 50 (2): 167 DOI: 10.1016/j.devcel.2019.06.012

Scientists have presented new findings that challenge established concepts of genetic inheritance. They have proven that somatic cells of the roundworm C. elegans influence heredity.

Scientists at the CECAD Cluster of Excellence in Aging Research of the University of Cologne have discovered that body cells which are in direct contact with the germ cells in the nematode Caenorhabditis elegans are responsible for controlling the stability of the genome in primordial germ cells (PGCs). All germ cells, including sperm and eggs, originate from primordial germ cells that form during early embryo development...