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AI tool reveals what attracts immune cells to tumors and what keeps them away

Immune cells (yellow) being attracted to a cancer cell (green).

Researchers at The University of Texas MD Anderson Cancer Center and collaborating institutions in Texas developed an artificial intelligence (AI) model that helps explain how immune cells find their way to specific locations in the body and why they avoid others. The findings could help scientists better understand cancer, autoimmune diseases and treatment response.

The study, published in Nature Biomedical Engineering, was co-led by Tao Wang, Ph.D., associate professor of bioinformatics and computational biology, and Linghua Wang, M.D., Ph.D., professor of genomic medicine, executive director and head of the Center for Cellular Language Intelligence, associate member of the James P. Allison Institute and focus area co-lead with the Institute for Data Science in Oncology.

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