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A chemical isolated from grape seed extract prolongs the lifespans of old mice by 9 per cent by clearing out their old, worn-out cells. The treatment also seems to make the mice physically fitter and reduces the size of tumours when used alongside chemotherapy to treat cancer.
The finding strengthens the case for future anti-ageing therapies that target senescent cells – aged cells that lose their ability to replicate and instead churn out substances that cause inflammation.
Senescent cells increase in number as we get older, and have been linked to various age-related conditions, including cardiovascular disease, type 2 diabetes and osteoporosis.
To find a substance that might destroy these cells, Qixia Xu at the...
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