Telobaits tagged posts

Novel Method to Accurately Measure Key Marker of Biological Aging

Singapore-led collaboration develops novel method to accurately measure key marker of biological ageing
Using home-grown designed telomeric-DNA sequences, called ‘Telobaits’, and highly-advanced DNA sequencing technology, scientists can now precisely determine the length of a single telomere from an individual. This technique could potentially be used to measure the impact of lifestyle or drug interventions to tackle ageing-related diseases. Credit: Dr Javier Koh, Duke-NUS Medical School

Telomeres—the caps at the ends of chromosomes that protect our genetic materials from the brunt of cellular wear and tear—are known to shorten and fray over time. Lifestyle, diet and stress can exacerbate this process, leading to early loss of telomere protection and increasing the chances of early aging and diseases, such as cancer and heart disease.

To date, approaches for measuring biological a...

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