Identification of fibrocartilage stem cells (blue) from the TMJ that spontaneously regenerate cartilage (red) when transplanted in vivo. Credit: Lab of Mildred C. Embree, DMD, PHD, Columbia University Medical Center
Columbia College of Dental Medicine researchers have identified stem cells that can make new cartilage and repair damaged joints. The cells reside within the temporomandibular joint (TMJ), which articulates the jaw bone to the skull. When the stem cells were manipulated in animals with TMJ degeneration, the cells repaired cartilage in the joint. A single cell transplanted in a mouse spontaneously generated cartilage and bone and even began to form a bone marrow niche...
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