tissue-engineered model of lung and trachea tagged posts

Scientists Develop Tissue-Engineered Model of Human Lung and Trachea

Scientists at Children’s Hospital Los Angeles have developed a tissue-engineered model of lung and trachea which contains the diverse cell types present in the human respiratory tract. Lung disease causes >200,000 deaths annually in the US. Although the lung is generally considered slow to respond to disease and injury, it does undergo regenerative processes, most of which are not fully understood. Building an understanding of these processes might lead to harnessing these innate mechanisms to help damaged lungs repair. A first step is a proper 3D model in which the disease process can be studied.

Previously, Grikscheit’s lab developed tissue-engineered small intestine (TESI) and showed that this regenerated tissue was fu...