Osteoarthritis is the most common form of joint disease, a condition that causes joints to become painful and stiff. It can happen to any joint when the cartilage cushioning the ends of bones breaks down or wears away. Currently, there are no approved drugs to slow or stop the underlying disease. But there is a promising development from an unexpected quarter—a blood thinner.
Researchers led by Chuan-ju Liu from the Department of Orthopedics and Rehabilitation at Yale University School of Medicine screened a library of nearly 1,000 approved drugs for compounds that could suppress the inflammatory signals underlying osteoarthritis.
Although inflammation ...
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