This is the delivery and activation of genes by gold nanorods. Gold nanorods coated with charged lipids efficiently bind to DNA and penetrate cells. The team designed an artificial gene that is turned on by heat generated by the gold nanorods upon exposure to near infrared light illumination.
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Kyoto University iCeMS
A new method efficiently transfers genes into cells, then activates them with light. This could lead to gene therapies for cancers. Mineko Kengaku, Tatsuya Murakami, and their colleagues from Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) have developed a new method that modifies the surface of nanorods, making them more efficient in transporting cancer-killing genes into cells.
The method involves coating gold nanorods, which produce heat when e...
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