traumatic brain injury tagged posts

This Groundbreaking Biomaterial Heals Tissues from the inside out

A beaker with tissue being spun
The biomaterial is based on a hydrogel that Christman’s lab developed. 

The material can be injected intravenously and has potential application in heart attacks, traumatic brain injury and more. A new biomaterial that can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair. The biomaterial was tested and proven effective in treating tissue damage caused by heart attacks in both rodent and large animal models. Researchers also provided proof of concept in a rodent model that the biomaterial could be beneficial to patients with traumatic brain injury and pulmonary arterial hypertension.

“This biomaterial allows for treating damaged tissue from the inside out,” said Karen Christman, a professor of bioengineering at the University of California...

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Surprising Culprit Worsens Stroke, TBI damage

In the aftermath of a stroke or traumatic brain injury (TBI), a group of amino acids that typically support brain function contribute significantly to the brain destruction that can follow both these injuries, scientists report.

The new study provides for the first time the surprising evidence that four common nonexcitatory amino acids that usually make proteins which are essential to brain function, instead cause irreversible, destructive swelling of both the astrocytes that support neurons and the neurons themselves, says Dr. Sergei Kirov, neuroscientist in the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia.

“There are many ways to kill neurons...

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