treat Alzheimer’s disease tagged posts

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells. In Alzheimer’s disease, the ability to make energy is compromised, and the connections between nerve cells (called synapses) eventually come apart and wither, causing new memories to fade and fail.

A Scripps Research team, reporting in the journal Advanced Science, has now identified the energetic reactions in brain cells that malfunction and lead to neurodegeneration...

TA-treatment enhanced neurogenesis and increased numbers of DCX positive cell numbers in the dentate gyrus of APP/PS1 mice. A: control group; B: APP/PS1 group; C: APP/PS1+TA group. Scale bar in image A: 100 μm. *** = P < .001 compared with the control group; ### = P < .001 compared with the APP/PS1 group. One-way ANOVA with Bonferroni repeated measures post hoc tests. N = 6 per group.

A drug developed for diabetes could be used to treat Alzheimer’s after scientists found it “significantly reversed memory loss” in mice through a triple action. The research, published in Brain Research, could bring substantial improvements in the treatment of Alzheimer’s disease through the use of a drug originally created to treat type 2 diabetes...