During breast cancer, some cancer cells will leave the tumor to invade into nearby tissues. In this new paper, Salk scientists find that the gene Sox10 is important in activating this local invasion. Left panel: Significant numbers of invasive cancer cells with Sox10 (red) in them can be found outside of the tumor (green cells, outlined). Right panel shows the invasive cells’ proximity to blood vessels (white).
Credit: Salk Institute
A team at the Salk Institute has identified a master switch that appears to control the dynamic behavior of tumor cells that makes some aggressive cancers so difficult to treat. The gene Sox10 directly controls the growth and invasion of a significant fraction of hard-to-treat triple-negative breast cancers.
Recently, the Salk lab led by Professor Geoffrey Wa...
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