umbilical cord blood tagged posts

Umbilical cord blood transplant with pooled stem cell product shows 96% survival and no GVHD in leukemia patients

A new way of using umbilical cord blood for treating blood diseases could make the treatment more accessible to patients who need a stem cell transplant. A Phase II clinical trial of patients undergoing a cord blood transplant plus a stem cell product derived from pooled cord blood units showed that 27 of 28 patients (96%) with leukemias and GVHD survived at least one year and none of the patients experienced severe acute or chronic graft-versus-host disease, which are common complications of stem cell transplantation.

The results have been published in the Journal of Clinical Oncology.

“This is the first time transplant patients received cells from what amounts to nine different human beings,” said the study’s principal investigator, Filippo Milano, MD, Ph.D...

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Exposure to Cadmium in the Womb linked to childhood Asthma and Allergies

Babies born with higher levels of cadmium in their umbilical cord blood may be more likely to develop childhood asthma and allergies, according to research presented at the European Respiratory Society International Congress.

Cadmium is known to be hazardous to human health and its use is restricted in the European Union, but it has been widely used, for example in batteries, pigments and as a coating for other metals. It is also present in tobacco and can enter the body via smoking or passive smoking.

Researchers say their findings lend support for tight controls over the use and disposal of cadmium.

The research was presented to the virtual conference by Professor Isabella Annesi-Maesano, research director at France’s Institut national de la santé et de la recherche médical...

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