weight-loss drug tagged posts

For people with painful knee osteoarthritis (OA) who are overweight or have obesity, everyday activities such as walking, climbing stairs and standing up from a chair can be difficult. In two Northwestern University–led Phase III clinical trials involving more than 1,000 participants combined, those taking the highest dose of retatrutide, a new experimental weight-loss injectable drug, lost about one-quarter of their body weight on average.

A pooled analysis of the studies found that about two-thirds of participants receiving retatrutide experienced at least a 50% reduction in knee pain, compared with 38% of those receiving placebo.

In addition to weight loss and pain relief, participants experienced other significant benefits, including reduc...